4.10: Mutation Effects
4.10: Mutation Effects
Sep 23, 2016
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SOLVED: MDM2p53Active TetramersCell CycleFigure: MDM2 and p53 signaling in response to DNA damage controls cell cycle progressionThe p53 and MDM2 proteins are involved in the DNA damage response pathway (Figure 1). In the absence of DNA damage, MDM2 mediates the degradation of p53. In the presence of DNA damage, p53 is not broken down and forms active tetramers that stimulate the expression of genes that block cell cycle progression.Red blood cells are produced by the division and differentiatio
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