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  1. MTHFR Gene Variant and Folic Acid Facts | Folic Acid | CDC

    May 27, 2025 · You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true.

  2. MTHFR Gene Mutation: Deficiency, Symptoms, Testing, Treatments

    Sep 9, 2024 · There are two common MTHFR mutations, known as C677T and A1298C. Having one copy of C677T or one copy of A1298C is not associated with health risks. Read on to …

  3. MTHFR mutation: Symptoms, testing, and treatment

    Aug 21, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may …

  4. MTHFR Gene Mutations: What You Need to Know - WebMD

    MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.

  5. Methylenetetrahydrofolate reductase - Wikipedia

    Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the …

  6. MTHFR Gene Mutation: Symptoms, Testing, and Treatments

    Feb 25, 2025 · MTHFR is a gene everyone has. Some mutations of the MTHFR gene may be associated with health problems and complications in pregnancy. Learn about determining …

  7. MTHFR Mutation Test: MedlinePlus Medical Test

    A MTHFR gene test uses a sample of your blood to look for two very common changes in a gene called MTHFR. A change in this gene is also called an MTHFR variant or MTHFR mutation.

  8. MTHFR Gene Mutations Explained: Symptoms, Risks & Testing …

    Jun 2, 2025 · Everything on MTHFR gene mutations, impact on health, symptoms, and testing. How MTHFR affects methylation, folate, and homocysteine—plus natural ways to manage it.

  9. MTHFR Gene Mutations and Disease - Verywell Health

    Nov 10, 2025 · MTHFR gene mutations are linked to many diseases to varying degrees, including heart disease, birth defects, Alzheimer's, and hypothyroidism.

  10. MTHFR Gene: Key Facts, Symptoms, and Treatment Options

    Mutations in this gene can lead to elevated homocysteine levels, which are linked to various health issues, including cardiovascular diseases and birth defects. This article explores the …