Hypoxia-inducible factor - Wikipedia
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. [1][2] They also respond to instances of pseudohypoxia, such …
HIF Global and Antarctica21 Renew Exclusive Alliance, Expanding the …
Jan 12, 2026 · The Zodiac boats of Antarctica21’s Magellan Explorer cruise will operate on synthetic gasoline produced using the power of Magallanes’ winds. Punta Arenas, Chile, January 12, 2026. …
Hypoxia Inducible Factors (HIFs) - Bio-Techne
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreased oxygen level in the cellular environment. Various isoforms and splice variants have been identified and their activities …
Hypoxia Inducible Factor - an overview | ScienceDirect Topics
Hypoxia-inducible factor (HIF) is defined as a key transcription factor that mediates physiological responses to low oxygen levels by regulating the expression of genes involved in processes such as …
The Role of HIF in Immunity and Inflammation - PubMed
Oct 6, 2020 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, …
Redefining the role of hypoxia-inducible factors (HIFs) in oxygen ...
Mar 16, 2025 · We propose an alternative model focused on understanding the dynamics of HIFs’ activity within its physiological context. Our model suggests that HIFs would not respond to but rather …
HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected …
HIF-1 and HIF-2 in cancer: structure, regulation, and therapeutic ...
Jan 18, 2025 · HIF-1 and HIF-2 are well known and widely described. Although these proteins share a high degree of homology, HIF-1 and HIF-2 have non-redundant roles in cancer. In this review, we …
JCI - HIF in the heart: development, metabolism, ischemia, and ...
Sep 1, 2021 · Cardiac development, metabolic tuning, and the response to ischemia are all regulated in part by the hypoxia-inducible factors (HIFs), central components of essential signaling pathways that …
The Hypoxia-Inducible Factor Pathway (HIF) | Haase Lab
HIF-1 and HIF-2 are the most extensively studied HIF transcription factors and facilitate oxygen delivery and adaptation to hypoxia by regulating a wide spectrum of cellular and tissue hypoxia responses.