CD7 ... CD7 (C luster of D ifferentiation 7) is a protein that in humans is encoded by the CD7 gene. [5]

CD7 is a protein found on the surface of certain cells in the human body. It is a transmembrane glycoprotein, meaning it spans the cell membrane and has sugar components attached.

Dec 8, 2025 · CAR7 products can be generated without gene editing by transducing T-cell subsets that are naturally CD7− or that have masked or sequestrated CD7 after expression of CAR7.

Because CD7 is also expressed on T-ALL and AML tumor cells, we examined whether CD7 expression in cell lines is the same as CD7 in human peripheral blood T cells and if it plays any significant role.

Nov 21, 2025 · CD7 is a protein found on the surface of certain immune cells, belonging to a family of molecules known as Cluster of Differentiation (CD) markers. This molecule is a single-chain …

CD7 is defined as a cell surface antigen expressed on approximately 30% of acute myeloid leukemia (AML) cells and nearly all T-cell leukemias, which complicates the production of CD7-directed CAR T …

Jan 14, 2026 · Complete information for CD7 gene (Protein Coding), CD7 Molecule, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium

CD7 is a transmembrane protein highly expressed in acute T-cell leukemia (T-ALL) and in a subset of peripheral T-cell lymphomas. Normal expression of CD7 is largely confined to T cells and natural …

Sep 18, 2025 · We identify CD7 as a tissue-specific regulator of terminally exhausted CD8 + T cells during chronic infection. CD7 expression progressively increases during exhaustion, reaching its …

Jun 19, 2024 · CD7 is a transmembrane protein primarily expressed on the surface of T cells and natural killer (NK) cells. It plays a significant role in the regulation and activation of the immune response.