Cell division is one of the most fundamental and complex processes underpinning life. In human cells, thousands of molecules ...

A newly discovered pair of stem cell lineages drives the formation of both tooth roots and the bone that anchors them. Understanding how these cells switch roles could pave the way for regenerating ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

This important work introduces a splitGFP-based labeling tool with an analysis pipeline for the synaptic scaffold protein bruchpilot, with tests in the adult Drosophila mushroom bodies, a learning ...

The study, “Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates,” was published in Cell Reports. In the study, first author Seth Fortmann, M.D., Ph.D.

When people think about health, they often focus on specific organs like the heart or brain. But many changes related to chronic conditions or ageing begin in the smallest units of your body — your ...

Scientists in China have unveiled a breakthrough way to mass-produce powerful cancer-fighting immune cells in the lab. By engineering early-stage stem cells from cord blood—rather than trying to ...

Volkswagen knows what it takes to make a great van, whether we're talking commercial goods-hauler or MPV-cum-weekend camper. Sometimes that means working with the aftermarket to create a versatile van ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...