The hereditary motor and sensory neuropathies (also known as Charcot–Marie–Tooth disease or CMT) are characterized by a length-dependent loss of axonal integrity in the PNS, which leads to progressive ...
Hereditary neuropathies are genetically heterogeneous and affect neurons and/or Schwann cells. Mutations in several different genes can lead to the same disease phenotype. Conversely, different ...
An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit ...
"Alterations in axonal membrane and channel function occur early in the disease course, prior to discernable large fibre involvement, and has the potential to be used as an early biomarker of ...
Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Peripheral ...
The latest reports come from 2 separate European groups. Dr C Metzler (University Hospital of Schleswig-Holstein, Luebeck, Germany) and colleagues told the British Society of Rheumatology meeting how ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback