. Tumor-associated macrophages (TAMs) and tumor-associated neutrophils (TANs) produce various proangiogenic growth factors and cytokines such as vascular endothelial growth factor (VEGF), tumor ...

A team from the Spanish National Cancer Research Centre (CNIO) has discovered a novel way in which tumor cells alter the ...

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses. A deficiency in the oxygen-carrying capacity ...

Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are ...

Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help ...

Scientists from the VIB–KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, have ...

A new nano-sized drug carrier that finds bone tumors and releases treatment exactly where it's needed is here to improve the precision and comfort of cancer therapy. Designed by a team of researchers ...

Angiogenesis inhibitors showed no increased risk of arterial dissections or aneurysms in metastatic colorectal cancer patients. The study involved 34,733 patients, with 195 cases matched to 1950 ...

Cancer specialists have long known that anemia, caused by a lack of healthy red blood cells, can arise when cancer metastasizes to the bone, but it’s been unclear why. A research team led by Princeton ...