Schematic representation of different strategies targeting TGF-β signaling for liver fibrosis therapy. TGF-β signaling inhibitors hold important therapeutic potential for hepatic fibrosis. Although ...

Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the ...

Transforming Growth Factor Beta (TGF‐β) signalling pathways are integral to a wide array of cellular processes, ranging from embryonic development to tissue homeostasis and immune regulation. TGF‐β ...

TCGFB, a private biotech founded by healthcare VC The Column Group, is tapping California biotech Surrozen to discover antibodies for idiopathic pulmonary fibrosis, according to a Nov. 4 release.

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...