Activating the cell surface receptor TREM2 rallies microglia to clear amyloid plaques. Can activating a kinase downstream of TREM2 do the same? Two groups of scientists say yes. In the October 26 Cell ...
Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that has long been thought to exclusively mediate signalling by receptors of the adaptive immune response (B cell receptors (BCRs) and Fc ...