Flow cytometry assay validation requires different analytical approaches in preclinical and clinical settings. A fit-for-purpose (FFP) strategy allows researchers to customize the validation to ...

Tuberculosis infection in chronic myeloid leukemia (CML) patients treated with imatinib. Background: The BCR-ABL fusion gene results from the translocation t(9;22). It is the hallmark of chronic ...

Quest expects the new blood test will support response monitoring in clinical trials.

Flow cytometry is an invaluable method for biomedical research. Since its development over 50 years ago, technology for flow cytometry has progressed rapidly, allowing for the detection of more and ...

Although established more than 30 years ago, the field of flow cytometry continues to grow and advance. It remains an indispensable tool for clinicians and researchers. The “Northwest Regional ...

Flow cytometry is a high throughput method of cell analysis that utilizes carefully designed flow systems to pass cells or other particles in a single file by a laser detector, allowing the size and ...

Flow cytometry is a way to look closely at the features of cells or particles. A sample of blood or tissue goes into a machine called a cytometer. In less than a minute, a computer can analyze ...

The escalating cost of developing drugs is due, in part, to time spent assessing compounds that fail further down the drug discovery process. As such, high-content analysis (HCA) is now emerging as ...

Human umbilical vein endothelial cells (HUVECs) were seeded at 1 × 10 4 cells per cm 2 in six-well plates. Treatment with TNF-α (2.5, 5 or 10 ng/ml) or lipopolysaccharide (0.5, 1 or 5 μg/ml) treatment ...