New research reveals that subtle chemical changes to proteins after synthesis play a critical role in determining ...

Protein modifications matter: Scripps Research showed post-translational modifications can dictate whether proteins bind to drugs, potentially guiding more selective therapy design. Hidden ...

Protein changes matter: Scripps Research showed that post-translational modifications can make proteins more or less responsive to drug-like molecules, affecting treatment success. Genetics meets ...

Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.

The focus of vertebrate studies has mainly been on canonical phosphorylation, but research indicates that phosphorylation of other non-canonical amino acids also regulates integral aspects of cell ...

At the University of Oxford, scientists have developed a nanopore technology that can identify three different post-translational modifications (PTMs) in individual proteins, even deep within long ...

Objectives Smoking is recognised as one of the strongest environmental risk factors for the development of rheumatoid ...