Breakthrough Discovery Could Make Pancreatic Cancer Respond to Chemo Again

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.
Fred Hutch

A disease driver of pancreatic cancer reveals a new Achilles heel

The use of chemotherapy to treat pancreatic ductal adenocarcinomas (PDACs) has mixed outcomes on disease progression. The complexity of PDACs acts as a key barrier to effective therapy development.
ascopubs.org

Real-World Validation of the Purity Independent Subtyping of Tumors Classifier for Informing Therapy Selection in Pancreatic Ductal Adenocarcinoma

Circulating Tumor DNA Genotyping of Intrinsic and Acquired Gene Alterations in Patients With Advanced Breast Cancer Receiving Palbociclib: Biomarker Results From POLARIS Study FOLFIRINOX (FFX) and ...
Morning Overview on MSN

Scientists uncover genetic switch that makes pancreatic cancer chemo-proof

Researchers at Duke-NUS Medical School have identified a molecular switch controlled by the protein GATA6 that determines whether pancreatic cancer cells respond to chemotherapy or become resistant.