Mass distribution of azithromycin to preschool children twice yearly for 2 years has been shown to reduce childhood mortality in sub-Saharan Africa but at the cost of amplifying macrolide resistance.

WATERTOWN, Mass.--(BUSINESS WIRE)--Macrolide Pharmaceuticals, a next-generation antibiotics company developing macrolides that are first-in-class with Gram-negative activity for a broad range of multi ...

LONDON, ON — In a retrospective study of >600,000 seniors, those who received a new prescription of a macrolide antibiotic (azithromycin, clarithromycin, or erythromycin) did not have a greater ...

NEWTON, Mass.--(BUSINESS WIRE)--Macrolide Pharmaceuticals, a new company with groundbreaking technology to develop novel antibiotics, completed a Series A financing of $22 million led by Novartis ...

Background: Many respiratory tract infections are treated with macrolide antibiotics. Regulatory agencies warn that these antibiotics increase the risk of ventricular arrhythmia. We examined the ...

Researchers from Niigata University and a University of Pennsylvania team have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to ...

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library—called V1M—contains chemical structures and computed ...

(HealthDay)—Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes, according to a study published online Dec. 13 in the Journal of Dermatology. Keisuke ...

According to a meta-analysis, long-term macrolide therapy at low doses could reduce acute exacerbations in patients with chronic obstructive pulmonary disease. Long-term macrolide therapy at low doses ...

A new study published in the journal BMJ in February 2020 reports that macrolide or penicillin antibiotic consumption in pregnancy could be linked to several adverse health outcomes in children. These ...