LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Researchers have found positive results in mouse models of severe allergy when treating them with an allergen-specific mRNA ...

Lipid nanoparticles (LNPs) have become the gold standard in non-viral gene delivery technologies, exemplified by the approval of the LNP messenger RNA (mRNA) vaccines against SARS-CoV-2. Since then, ...

Engineered nanoparticles can improve cancer immunotherapy by delivering drugs, antigens, and genetic payloads with greater ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological information. In order for them to work in the body, they must enter the cells ...

Lipid-based nanoparticles (LNPs) are becoming an essential platform in pharmaceutical research and manufacturing. They’re used to improve the delivery of mRNA, enhance the absorption of poorly ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a ...

The findings, demonstrated in mouse models and isolated human brain tissue, could expand treatment options for neurological and psychiatric diseases New York, NY [February 17, 2025]—Scientists at the ...