In the passive avoidance test, at the learning trial (day 0), mice of all groups entered the dark compartment, and there were no significant differences among the animals. However, in the testing ...

For very long, researchers have hypothesized that lipopolysaccharide (LPS) endotoxins shed from the outer membrane of Gram-negative bacteria, e.g., gut-resident Bacteroides fragilis and Escherichia ...

We report here for the first time that high-fat feeding augments plasma LPS at a concentration sufficient to increase body weight, fasted glycemia, and inflammation. LPS infusion in normal diet-fed ...

“This is a very interesting paper. It addresses a big overall question of how does the immune system distinguish between infection and non-infectious tissue damage,” said immunologist Cynthia Leifer ...