This article is based on a poster originally authored by Chris Bohl, Ken Brouwer, Karissa Cottier, Scott Heyward, Courtney Noah, Brian Ogilvie, and BioIVT. Several reports in the literature have ...

(A) Transgene structures for the expression of the exogenous FLAG-tagged CYP2D6 protein or the IRES-based co-expression of the human hepatic CYP2D6 and GFP proteins. (B) Phase contrast images of the ...

BioIVT offers a variety of hepatocyte test systems, including immortalized or primary cells, fresh or cryopreserved, and animal or human hepatocytes, all available in the format of your choice.

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

In early-stage drug discovery, in vitro models are essential for generating clinically relevant data that expedite the progress of potential therapeutics into clinical trials. However, most ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is ...

The liver is the only internal organ that can regenerate itself. Remarkably, even if 70 percent of the liver is removed, its tissue can regrow into a full-sized organ within a matter of months. By ...