For decades, the standard explanation for autoimmune diseases like rheumatoid arthritis has rested on two pillars: inherited ...

As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children's Hospital, published in Cell, finds that the brain's resident immune cells, ...

What causes autoimmune disease? A new study finds that somatic mutations in immune checkpoint genes like PDL1 trigger the immune system to attack the body.

A new Nature study suggests DNA mutations in immune cells may drive autoimmune diseases by removing immune system brakes, offering clues for targeted treatments.

SYNGAP1 encephalopathy is a rare genetic disorder for which there is no treatment. It causes epilepsy, intellectual ...

From decoding hidden genetic mutations to testing novel treatments, scientists are making real progress against rare inherited eye diseases. These breakthroughs could mean earlier diagnoses, targeted ...

Wounded and elderly patients are being evacuated by train from embattled east Ukraine - Copyright AFP Ishara S. KODIKARA Wounded and elderly patients are being ...

Diseases like cancer or neurodegeneration are known to arise from genetic misfires. But treating such complex conditions hasn ...

Our DNA is compacted and arranged into chromosomes, most of which are shaped like X’s. The ends of the chromosomes' arms are protected with caps known as telomeres. Telomeres are made up of highly ...

Some blood cancers move with eerie patience. A patient can feel well for years, their blood counts looking steady, their ...

Mutations in the ATP‐binding cassette transporter A3 (ABCA3) gene are increasingly recognised as a significant contributor to interstitial lung disease (ILD) in infants and children. ABCA3 plays a ...