Virginia Tech researchers are investigating how overloaded mitochondria in the brain’s memory circuits may spark early Alzheimer’s damage. Their work focuses on calcium signaling and how it might ...

This study illustrates the spatiotemporal dynamics of neuron subtype changes within the entorhinal cortex–hippocampal circuit during Alzheimer’s disease progression. EC-stellate neurons progressively ...

Brain iron measured by quantitative susceptibility mapping MRI predicted cognitive decline in healthy older adults. Higher magnetic susceptibility in two brain regions was tied to a higher risk of ...

Why do memories fade in Alzheimer's disease—and can they be restored? University of California, Irvine researchers have uncovered a key mechanism underlying memory loss, showing for the first time ...