ONCR-719 is uniquely engineered to use the Epidermal Growth Factor Receptor (EGFR/EGFRvIII) for viral entry, which is highly expressed in glioblastoma multiforme (GBM); data show that the canonical ...
Researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and ...
The EDMV vector was designed to express the large Cas9 protein and a sgRNA containing a customized spacer sequence. Infection of N. benthamiana and tobacco (N. tabacum) with the viral vector yield ...