AFTX-201 is designed using Affinia's proprietary capsid engineered for efficient cardiac transduction at doses that are 5-10-fold lower than doses of gene therapies using conventional capsids WALTHAM, ...

The FDA has granted Fast Track designation to AFTX-201 for the treatment of BAG3-associated dilated cardiomyopathy.

The designation aims to accelerate medicines that address unmet medical needs in serious conditions.

Fashion designer Rohit Bal has been battling for his life at Medanta Hospital in Gurugram. Surviving a major heart attack in 2010, Bal (62) now faces the challenges of a rare medical condition known ...

Idiopathic dilated cardiomyopathy (IDC) is defined by the presence of left ventricular dilatation and systolic dysfunction in the absence of an underlying cause, such as hypertension, valve disease or ...

Scientists at the CNIC and Hospital Universitario Puerta de Hierro in Majadahonda have developed a software application that predicts the likelihood that a case of dilated cardiomyopathy is caused by ...

Two new studies outline the causes of dilated cardiomyopathy, an autoimmune reaction that slowly destroys the heart (pages 1477–1483 and 1484–1490). You have full ...

Numerous heart conditions are on rise in modern times due to a mix of genetic, lifestyle and environmental factors. A heart condition that has come into focus after fashion designer Rohit Bal was ...

Peripartum cardiomyopathy shares some clinical features with idiopathic dilated cardiomyopathy, a disorder caused by mutations in more than 40 genes, including TTN, which encodes the sarcomere protein ...

Colored x-ray shows enlargement of the left ventricle (yellow) in a patient with cardiomyopathy. Routine testing helps identify the disease and lowers the risk of sudden death, but prompt referral to ...

Fundraising efforts are underway for a 4-year-old Vermilion girl who must undergo heart surgery. Brinley Wyczalek has been hospitalized at Cleveland Clinic Children’s for over 100 days, awaiting a ...