LMU researchers decipher how an enzyme modifies the genetic material in the cell nucleus. Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin.

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

From The Bedalov Lab, Human Biology and Translational Science and Therapeutics Divisions Thus, the team began this current study with a scavenger hunt for a nucleosome-modifying enzyme which could ...

The Gates lab studies the intersection between metabolism, chromatin, and gene regulation. We aim to discover how metabolite signaling to chromatin impacts cell and tissue function in health and ...

The Gates lab studies the intersection between metabolism, chromatin, and gene regulation. We aim to discover how metabolite signaling to chromatin impacts cell and tissue function in health and ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...