Nicotine withdrawal induces behavioral symptoms such as tremors and shaking. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine significantly reduces ...

The cholinergic interneurons were found to be involved in the loser effect, where mice became less dominant after losing competitions, moving down the social rankings. Surprisingly, these same brain ...

This is a preview. Log in through your library . Abstract Emerging studies indicate that striatal cholinergic interneurons play an important role in synaptic plasticity and motor control under normal ...

Investigators led by D. James Surmeier, Ph.D., the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in ...