Researchers identified a chaperone protein, Funes, that triggers controlled amyloid formation in fruit fly neurons to stabilize long-term memories. The study provides the first direct evidence that ...

Discover how amyloid proteins help form long-term memories according to new research from the Stowers Institute.

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom ...

A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The ...

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control ...

Heat shock proteins (HSPs) and molecular chaperones are fundamental to cellular proteostasis, ensuring proteins achieve and maintain their functional conformation while preventing misfolding and ...