An international multidisciplinary team has demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study, published in the ...

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the ...

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing "copilot" ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Amanda McQuade and Nathaniel Robichaud discuss how integrated proteomic and transcriptomic profiling can reveal cellular ...

As published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR ...

CRISPR activation restores FLNC expression and reverses cardiac electrical abnormalities in mice carrying a truncating variant of the gene • The study was led by researchers at the Centro Nacional de ...