Periventricular leukomalacia (PVL), the major substrate of neurologic deficits in premature infants, is associated with reduced white matter volume. Using immunomarkers of axonal pathology [β-amyloid ...

Neurons require specialized mechanisms of motor-facilitated signal transport for communication along long axonal distances to the cell body and the nucleus. Recent evidence suggests that the early ...

The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Traumatic axonal injury is the most common consequence of head trauma and is associated ...

The presence of axonal transections in patients with very short disease duration implies that axonal transection occurs in MS lesions at a very early stage of the disease. These 2 studies in ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — Diffuse axonal injury-type lesions in postoperative MRI can predict poor outcomes for children ...

A new report examined optic nerve lesion length, measured on brain magnetic resonance imaging, at the acute phase of ON in 51 individuals. Optic nerve lesion length was significantly associated with ...

Treatment with investigational evobrutinib reduced SEL volume compared with placebo, with the highest effect seen with 75 mg twice daily (P=0.047), reported Douglas Arnold, MD, of NeuroRx Research in ...

My laboratory studies plasticity in the adult nervous system. We are interested in the ways in which the chemistry of the adult nervous system can change and the functional consequences of such ...

Two different pathological mechanisms have been suggested to underlie adult-onset leukoencephalopathy with axonal spheroids (ALAS). Pathological studies have suggested that ALAS involves primary ...

New research finds that adult neurons can still regenerate as long as 15 months after a spinal cord injury. The study, published by Cell Press in the October 29th issue of the journal Neuron, ...

My laboratory studies plasticity in the adult nervous system. We are interested in the ways in which the chemistry of the adult nervous system can change and the functional consequences of such ...