Structure and the tethered activation mechanism of aGPCRs. (A) The basic structure of aGPCRs. This article highlights the critical role of mechanosensitive aGPCRs in human health and disease, setting ...
The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
In this international study, the scientists showed that one of the adhesion G protein-coupled receptors – GPR133 – is activated by the androgenic steroid hormone 5α-DHT. Created in BioRender. In this ...
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