Figure 2: Intermolecular interactions between ACP and LpxD. Figure 4: Molecular basis for the ordered-sequential reaction mechanism and involvement of ACP in lipid-product release. Site-directed ...

Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is a genetic condition that prevents the body from breaking down fat stores for energy. It can be fatal without early diagnosis and treatment.

Acyl fluorides are organic compounds that contain a fluorine atom in their structure. These compounds have recently gained much attention in transition-metal catalysis due to their stability and ...

The enzyme acyl–coenzyme A:cholesterol acyltransferase (ACAT) esterifies cholesterol in a variety of tissues. In some animal models, ACAT inhibitors have antiatherosclerotic effects. We performed ...

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us. The more scientists can identify and classify the molecules involved in ...

Very long-chain acyl-CoA dehydrogenase deficiency (VLCAD), a rare inherited genetic condition, is caused by mutations in the ACADVL gene. It is associated with a disorder in fatty acid metabolism and ...